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Not all topics (eg, economic aspects of pediatric HTN) were appropriate for the PICOT format.A third and final search was conducted at the time the Key Action Statements (KASs) were generated to identify any additional relevant articles published between August 2015 and July 2016.(See Table 1 for a complete list of KASs.)A detailed description of the methodology used to conduct the literature search and systematic review for this clinical practice guideline will be included in the forthcoming technical report.

These guidelines include 30 Key Action Statements and 27 additional recommendations derived from a comprehensive review of almost 15 000 published articles between January 2004 and July 2016.Each Key Action Statement includes level of evidence, benefit-harm relationship, and strength of recommendation.This clinical practice guideline, endorsed by the American Heart Association, is intended to foster a patient- and family-centered approach to care, reduce unnecessary and costly medical interventions, improve patient diagnoses and outcomes, support implementation, and provide direction for future research.Next, 2 subcommittee members and the epidemiologist conducted full-text reviews of the selected articles.Although many subcommittee members have extensively published articles on topics covered in this guideline, articles were not preferentially selected on the basis of authorship.

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Implementation tools for this guideline are available on the AAP Web site (https://org/en-us/about-the-aap/Committees-Councils-Sections/coqips/Pages/Implementation-Guide.aspx).

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